Revelation 16:3-4

 "And behold, I am coming quickly. 

Blessed is he who heeds the words of the prophecy of this book."     

Revelation 22:7  NASB

The second angel poured out his bowl on the sea, and it turned into blood like that of a dead person, and every living thing in the sea died. The third angel poured out his bowl on the rivers and springs of water, and they became blood.

and every living thing in the sea died 
Exodus 7:17-18  " 'This is what the LORD says: By this you will know that I am the LORD: With the staff that is in my hand I will strike the water of the Nile, and it will be changed into blood. The fish in the Nile will die, and the river will stink; the Egyptians will not be able to drink its water.' " 
Revelation 8:8-9  The second angel sounded his trumpet, and something like a huge mountain, all ablaze, was thrown into the sea. A third of the sea turned into blood, a third of the living creatures in the sea died, and a third of the ships were destroyed.
Revelation 11:6  They (the two witnesses) have power to shut up the heavens so that it will not rain during the time they are prophesying; and they have power to turn the waters into blood and to strike the earth with every kind of plague as often as they want.

The third angel poured out his bowl on the rivers and springs of water 
Revelation 8:10  The third angel sounded his trumpet, and a great star, blazing like a torch, fell from the sky on a third of the rivers and on the springs of water--...
Exodus 7:19-21  The LORD said to Moses, "Tell Aaron, 'Take your staff and stretch out your hand over the waters of Egypt--over the streams and canals, over the ponds and all the reservoirs--and they will turn to blood.' Blood will be everywhere in Egypt, even in vessels of wood and stone." Moses and Aaron did just as the LORD had commanded. He raised his staff in the presence of Pharaoh and his officials and struck the water of the Nile, and all the water was changed into blood. The fish in the Nile died, and the river smelled so bad that the Egyptians could not drink its water. Blood was everywhere in Egypt. 
Psalm 78:42-44  They did not remember his power--the day he redeemed them from the oppressor, the day he displayed his signs in Egypt, his wonders in the region of Zoan. He turned their river into blood; they could not drink from their streams.

(parentheses are mine)

Scriptures taken from the Holy Bible, New International Version® NIV®, Copyright© 1973, 1978, 1984, 2011 by Biblica, Inc.® Used by permission. All rights reserved worldwide. 
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